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This idea has significant implications because the aromatic and heterocyclic hydrocarbon compounds found in the smoke of tobacco cigarettes can be transformed into carcinogenic compounds as an end product by inducible enzyme systems found in Candida species 111,112

C Lung cancer was a rare disease until smoking became common in the 20th century

9 -THC can also impair the phagocytic activity of M2 macrophages [117]

However, when THC is consumed in excessive amounts, it can overwhelm the endocannabinoid system, leading to an imbalance in neurotransmitters

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